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Arch Dermatol 114:895896 Sutton RL (1916) An unusual variety of vitiligo (leukoderma acquisitum centrifugum)

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Regular review of weight loss progress, typically every three months, allows assessment of treatment response and consideration of whether continuation is appropriate according to NICE TA875, which recommends discontinuation if less than 5% weight loss is achieved after six months at the maintenance dose